HOT HMV trial


Benefits in using home oxygen therapy (HOT) in addition to home mechanical ventilation (HMV) in patients with COPD and chronic hypercapnia (116 patients).1


Median admission-free survival:


1.4 months


4.3 months

1.  Murphy PB, Rehal S, Arbane G, et al. Effect of home noninvasive ventilation with oxygen therapy vs oxygen therapy alone on hospital readmission or death after an acute COPD exacerbation: a randomized clinical trial. JAMA. 2017;317(21):2177-2186.

Integrated COPD Care Initiative


2017 pilot program designed to increase visibility into post-acute care by deploying evidence-based care strategies, pathways and processes (>890 patients):2

  • Care transition management
  • Care coordination
  • Patient engagement

80% reduction

in 30-day COPD readmissions

~$1.3 million saved

70% reduction

in 30-day all-cause readmissions

~$4.4 million saved

2.  Philips Respironics. The Integrated COPD Care Initiative. PDF file. 2018. Koninklijke Philips N.V. Available at:

Barnes study


Evaluate the benefits of NIV usage and a post-acute, integrated disease management approach for COPD patients (398)3

80% reduction

in hospital readmissions

$15.3 million saved


82% 1-year survival rate
3.  Coughlin S, Liang WE, Parthasarathy S. Retrospective Assessment of Home Ventilation to Reduce Rehospitalization in Chronic Obstructive Pulmonary Disease. J Clin Sleep Med.  2015 Jun 15;11(6):663-70.

Value in health study


Evaluate the economic impact of leveraging home NIV, as part of a multifaceted intervention program for severe COPD.4

Hospital base case (250 patients)


saved over 30 days


saved over 90 days

Payer base case (100,000 patients)

$326 million

saved over 3 years (versus no NIV)

$1.04 billion

saved over 3 years (versus respiratory assist device)

4.  Coughlin S, Peyerl FW, Munson SH, Ravindranath AJ, Lee-Chiong TL, Cost Savings from Reduced Hospitalizations with Use of Home Noninvasive Ventilation for COPD. Value in Health. 2017;20(3):379-387. dio:10.1016/j.jval.2016.09.2401.