Initially trained in Anesthesiology, Professor Muir moved to Medical Intensive Care and later in Pulmonology where he was nominated Professor in the early 80’ in Amiens University Hospital. After a few years he moved to Rouen University Hospital to become head of the Pulmonology Department where he created an RICU and a sleep laboratory in the early 90’. In 2000 he founded in collaboration with ENT, intensivists and rehabilitation researchers the Rouen University Respiratory Handicap Research Group EA 3830 that he directed for 8 years. In parallel, he contributed to develop a respiratory home care services association in Normandy inside the network of ANTADIR, National Federation of which he became President. He was also President of the National French Society of Pulmonology (SPLF) and secretary of ERS NIV group. For many years, he has been involved in research devoted to respiratory assistance in acute and chronic failure, especially concerning noninvasive ventilation. He was at the origin of the A40 multicenter French study that Dr Maxime Patout will be presenting in this session. Recently retired, Professor Muir is still involved in home respiratory assistance as the President of ADIR, regional home care services association of Normandy.