EEG Neuroimaging

High density EEG

Enhance your understanding of the electrical activity in each epilepsy case

See more with high density EEG
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Demonstrated value in epilepsy presurgical planning

Studies show...

 
  • >90% likelihood of positive outcome with concordant high density (HD) ESI and MRI localization1

 

  • 85% concordant localization with icEEG spikes2

 

  • 6.4x more likely to predict better surgical outcome compared to MRI, PET and SPECT1
 
  • Where MRI, PET and SPECT failed to provide adequate ictal localization, HD ESI predicted positive surgical outcomes in 6/10 patients3
 
  • HD EEG, in contrast to 10-20, demonstrates equivalent source localization accuracy to MEG source localization4

Capture spikes missed by 10-20 EEG

 

Higher spatial sampling with high density EEG technology enables higher resolution and allows you to detect more spikes, more activity surrounding each spike, and important information about spike propagation that sparse array can miss, enhancing your confidence in diagnosis and treatment.

  • Whole head, high density EEG provides up to 8x greater sampling density.  2x more spikes detected than 10-20 EEG (relative to icEEG).2
 
  • Allows you to non-invasively capture activity from anterior, medial and basal sources that can be missed in conventional 10-20 EEG.
 
  • In one series, HD EEG was shown to capture 100% of anterior, medial and basal temporal lobe spikes whereas sparse array captured only 10%.2
Net adult

Spikes visible in icEEG...

can be invisible in 10-20......

but visible with HD EEG2

Spikes visability

High density electrical source imaging clinical workflow

Net application
Number 1

Acquire

  • 256 electrodes for higher spatial resolution
  • Designed to improve patient compliance and clinic efficiency
Scalp activity
Number 2

Review

  • Designed for intuitive review of high density EEG data
  • Enables easy determination of the area of scalp activity spikes using the voltage map and topo plot
Geo-source-picture
Number 3

Visualize

  • GeoSource 2 software provides integrated source imaging
  • Enables fast visualization to support your diagnosis and streamline your workflow
  • Visualize brain activity on an advanced MRI-based atlas head model

1. Lascano A.M., Perneger T., Vulliemoz S., Spinelli L., Garibotto V., Korff C.M., Vargas M.I., Michel C.M., Seeck M. (2016). Yield of MRI, high-density electric source imaging (HD-ESI), SPECT and PET in epilepsy surgery candidates. Clin Neurophysiol 127: 150–155.

2. Yamazaki M., Terrill M., Fujimoto A., Yamamoto T., Tucker D.M. (2012). Integrating dense array EEG in the presurgical evaluation of temporal lobe epilepsy. ISRN Neurol 2012: 924081.

3. Holmes M.D., Tucker D.M., Quiring J.M., Hakimian S., Miller J.W., Ojemann J.G. (2010). Comparing noninvasive dense array and intracranial electroencephalography for localization of seizures. Neurosurgery 66: 354–362.

4. Klamer S., Elshahabi A., Lerche H., Braun C., Erb M., Scheffler K., Focke N.K. (2015). Differences between MEG and high-density EEG source localizations using a distributed source model in comparison to fMRI. Brain Topogr 28: 87–94.

 

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