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Lung cancer: a business and healthcare imperative

  • By
  • November 13 2025
  • 3 min read

November marks Lung Cancer Awareness Month with a white ribbon – a crucial opportunity to spotlight the leading cause of cancer death worldwide and reinforce the importance of early detection, innovative technology and strategic collaboration. Lung cancer remains the deadliest cancer globally, claiming more lives than breast, prostate and colorectal cancers combined.1 The message for organizational leadership is clear: lung cancer risk extends to anyone with lungs, making awareness and action a universal mandate within our communities and companies.

At-a-glance:

  • Lung cancer is the leading cause of cancer death worldwide, making awareness, early detection and access to screening a universal imperative.
  • Advances in precision medicine and genomic testing have improved lung cancer care, enabling targeted therapies and underscoring the need for routine molecular diagnostics in clinical practice.
  • Global adoption of low-dose CT (LDCT) screening is improving early detection and outcomes – highlighting the importance of leadership, collaboration and investment in scalable, evidence-based screening programs.
4D medical imaging

This month, the white ribbon calls us to focus on education, advocacy and leveraging breakthroughs in early detection.

Understanding lung cancer: the landscape

Lung cancer is not a monolith. Medical experts classify it into two primary types based on cellular characteristics and treatment considerations:

Small cell lung cancer (SCLC)

Fast-growing and highly aggressive, SCLC accounts for about 15% of cases and is strongly associated with a history of smoking.2

Non–small cell lung cancer (NSCLC)

Representing 85% of cases, NSCLC advances more slowly and is further split into subtypes:

  • Adenocarcinoma: Originates in mucus-secreting cells; the most common form, especially among non-smokers.
  • Squamous cell carcinoma: Begins in the lining of the airways and is typically linked to smoking.
  • Large cell carcinoma: A less common form that can appear throughout the lung.3

Beyond traditional risk factors

Historically, smoking and environmental exposures dominated lung cancer risk models. But that paradigm is shifting. Increasingly, clinicians are diagnosing lung cancer in patients with no known risk factors — non-smokers, younger individuals and those without occupational or environmental exposure histories.4

This underscores the critical importance of awareness, vigilance and equitable access to early detection technologies. Lung cancer is no longer confined to “high-risk” groups. It’s a public health imperative that requires proactive screening, research and education across all demographics.

Precision medicine and the genomic revolution

In recent years, lung cancer management has been transformed by discoveries in genomics and precision oncology. Over half of all NSCLC cases exhibit identifiable genetic mutations – such as KRAS, EGFR, ALK, MET, RET, BRAF and ROS1 – that can be targeted with highly effective therapies. For business leaders in healthcare, investing in diagnostic infrastructure and advocating for routine molecular testing at diagnosis are critical steps toward personalized, more effective patient care.

Genomic landscape at a glance

  • KRAS: Represents the largest share of actionable mutations in NSCLC.
  • EGFR: Especially prevalent in non-smokers, with highly effective targeted treatments available.
  • ALK, MET, RET, BRAF, ROS1: Together, these mutations offer multiple opportunities for precision intervention, improving both survival and patient quality of life.

The shift from generalized to personalized therapy underscores the need for health systems and providers to integrate comprehensive molecular diagnostics into lung cancer pathways as a standard of care.5

Lung cancer graph

Global adoption of low-dose CT screening

Early detection is the linchpin for improving lung cancer outcomes. The advent of low-dose CT (LDCT) scanning has proven transformative. The U.S. Preventive Services Task Force recommends annual LDCT screening for adults aged 50–80 with a smoking history, resulting in marked increases in early-stage diagnoses and survival rates.6

Australia in 2025 and Germany in 2024 launched national LDCT screening programs, joining the U.S. and several Asian countries – including South Korea, Japan and China – in expanding access to life-saving early detection. 7 8 9 For executives in healthcare and policy, supporting broad implementation of LDCT screening is both a clinical imperative and a sound investment in population health.

Philips' commitment to advancing early detection

Philips stands at the forefront of lung cancer screening innovation. Philips has specific solutions which harness AI-enabled CT image analysis and aim to streamline diagnostic workflows to support clinicians in identifying lung disease at its earliest, most treatable stages. By combining imaging intelligence, informatics and actionable insights, Philips partners with healthcare systems worldwide to implement scalable, evidence-based lung cancer screening programs.

These initiatives not only enhance the accuracy of diagnosis but help standardize and optimize care on a global scale. For organizations seeking to improve outcomes and reduce the burden of late-stage cancer, technology-driven early detection is essential.

Call to action: leadership, awareness and collaboration

Lung Cancer Awareness Month challenges businesses, healthcare systems and communities to remove stigma, advocate for equitable access to screening and diagnostics, and invest in research that unlocks progress against this deadly disease. Strategic collaborations between technology innovators, clinicians, policymakers and patient advocates are vital for closing gaps in care and delivering on the promise of precision medicine.

Now is the time for decisive leadership – by prioritizing early detection, supporting groundbreaking technologies and fostering a culture of awareness, organizations can help shape a future where early, data-driven lung cancer care is accessible for all.

Featuring
Heather Chait
AI Ecosystem Lead
Philips, Chicago
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Footnotes
  1. American Cancer Society. What Is Lung Cancer? Cancer.org. Updated 2024
  2. https://www.yalemedicine.org/conditions/small-cell-lung-cancer
  3. Cleveland Clinic. Non-Small Cell Lung Cancer (NSCLC): Symptoms, Diagnosis & Treatment. ClevelandClinic.org. Updated 2025
  4. https://pmc.ncbi.nlm.nih.gov/articles/PMC11014425/
  5. Zhang C, et al. “Targeted therapies for non-small cell lung cancer: an evolving landscape.” Biomarker Research. 2024;12(1):66. BiomarkerRes.BiomedCentral.com
  6. U.S. Preventive Services Task Force. “Screening for Lung Cancer: U.S. Preventive Services Task Force Recommendation Statement.” J Natl Compr Canc Netw. 2025;23(1):e250002. JNCCN.org.
  7. Australian Department of Health and Aged Care. National Lung Cancer Screening Program to commence 1 July 2025.I-MED.com.au.
  8. Federal Joint Committee (G-BA). “Germany launches low-dose CT screening for smokers to detect lung cancer early.” Market Access Today. June 18 2025. MarketAccessToday.com.
  9. de Koning HJ, et al. “International expansion of low-dose CT lung cancer screening.” Eur J Cancer. 2025;210:45-50. EJCancer.com
Disclaimer
The opinions and clinical experiences presented herein are specific to the featured topics and are not linked to any specific patient and are for information purposes only. The medical experience(s) derived from these topics may not be predictive of all patients. Individual results may vary depending on a variety of patient-specific attributes and related factors. Nothing in this article is intended to provide specific medical advice or to take the place of written law or regulations.