Tumor Ablation using Cone Beam CT and XperGuide
Image-guided therapy

Biopsy and tumor ablation

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Highly accurate needle interventions with Cone Beam CT

Lesion heterogeneity and lack of conspicuity limit the quality of specimens as well as the feasibility of biopsies when performed under ultrasound or conventional CT. Our needle navigation technology with CBCT increases precision, and enables the targeting of smaller (<=1 cm) or heterogeneous lesions more accurately with less needle repositioning and at lower dose than conventional CT.1, 2

Philips XperGuide Ablation

Advanced planning and guidance for tumor ablation

Performing successful tumor ablations, without compromising adjacent tissue, requires a clear understanding of the tumor size, the specific needle's ablation area, and the path to the target.

Demonstrated results in needle interventions with Cone Beam CT

  1. 17%

    reduction in procedure time with Azurion3

    17%

    reduction in procedure time with Azurion3

    This is just one of the many improvements in lab performance achieved by the Interventional Vascular Department at St. Antonius Hospital after installing the Azurion system. The impressive results achieved in this first Azurion lab performance study have been verified by an independent third party.

  2. 2x

    more accurate needle positioning compared to conventional CT1

    2x

    more accurate needle positioning compared to conventional CT1

    Accuracy, defined as the difference between planned and final needle positions, was two times more accurate for the Cone-Beam CT group, compared with conventional CT.

  3. 6x

    less repositioning compared to conventional CT1

    6x

    less repositioning compared to conventional CT1

    The mean number of needle repositions in the Cone-Beam CT group was six times less compared with conventional CT.

  4. 29%

    lower skin dose compared to conventional CT1

    29%

    lower skin dose compared to conventional CT1

    The average skin entry dose was 29% lower with Cone-Beam CT than with conventional CT.

Comprehensive approach to biopsy and ablation supports successful outcomes

Percutaneous ablation is a well-established minimally invasive tumor treatment. To perform a complete procedure and reduce the chances of surrounding tissue damage, it’s critical to define tumor boundaries and decide on needle characteristics, the number of needles and the corresponding needle trajectory. Navigating accurately to the lesion increases the opportunity for success and reduces risk of biopsy or ablation complications. 3D imaging with live guidance can be used to (re)position and advance the needle under low dose and verify the treatment endpoint while the patient is on the table.

Decide, guide, treat and confirm

  • Align a pre-procedural image with an intra-procedural Cone Beam CT (CBCT) image using DualView. Plan your needle path with XperGuide Ablation*
  • Optimize the needle position for effective ablation with XperGuide Ablation
  • Monitor your needle insertion at low dose with ClarityIQ. Have live trajectory guidance with XperGuide
  • Confirm the completeness of your ablation with SmartCT Soft Tissue

Advances for biopsy and ablation

  • SmartCT Soft Tissue is augmented with step-by-step guidance and advanced 3D visualization and measurement tools, accessible on the touchscreen module at tableside
  • XperGuide offers highly accurate live image guidance of each needle to a targeted position by overlaying pre-planned trajectories with fluoroscopic imaging2
  • DualView overlays a pre-procedural 3D image (CT/MR/PET-CT) on an intra-procedural CBCT Dual so you can better visualize lesions and access critical input for needle planning
  • Post-ablation CBCT demonstrates the extent of tumor coverage and confirms treatment completeness

Image gallery

  • Philips needle navigation technology with CBCT increases precision
    Philips needle navigation technology with CBCT increases precision
  • Better visualize the lesions and access critical input for needle planning.
    Better visualize the lesions and access critical input for needle planning
  • Optimize the needle position for effective ablation with XperGuide Ablation
    Optimize the needle position for effective ablation with XperGuide Ablation
  • Align a pre-procedural image with an intra-procedural CBCT image using Dualview
    Align a pre-procedural image with an intra-procedural CBCT image using Dualview
  • XperGuide Ablation provides comprehensive assistance for treatment planning and live needle guidance
    XperGuide Ablation provides comprehensive assistance for treatment planning and live needle guidance

What we see is that our workflow actually became much smoother, and this meant that we were able to perform our procedures at quicker speed.

Marco van Strijen, M.D.
St. Antonius hospital Nieuwegein, the Netherlands
alt text for testimonial

Enabling technologies

  • Two clinicians viewing screens using ClarityIQ during interventional procedure.

    ClarityIQ Technology

    ClarityIQ technology delivers significantly lower dose across the clinical area, patients, and operators.

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Documentation

Onco suite - Critical insights for superior care in interventional oncology
PDF|(1.44 MB)
Azurion 7 with FlexArm Product Brochure
PDF|(700.01 KB)
Azurion with SmartCT Product Brochure
PDF|(2.43 MB)
Footnotes
  1. Cone Beam vs Conventional CT Navigation for Image-Guide Biopsy; N Abi-jaoudeh et al (2016), J VascIntervRadio l27:1342– 1349.
  2. Percutaneous transthoracic needle biopsy of small (1 cm) lung nodules under C-arm cone-beam CT virtual navigation guidance; Ji Yung Choo Eur Radiol (2013) 23:712–719.
  3. Philips whitepaper 12nc 4522 991 30501; Reduction of procedure time by 17% with Philips Azurion in independently verified study; https://www.usa.philips.com/healthcare/case-study/philips-azurion-lab-performance-study. Results are specific to the institution where they were obtained and may not reflect the results achievable at other institutions.
  4. Floridi C, et al. Percutaneous needle biopsy of mediastinal masses under C-arm cone beam CT guidance: diagnostic performance and safety. Medical Oncology. 2017; 34(4):1-7.
Disclaimer
* XperGuide ablation is a feature of XperGuide.
Product availability is subject to country regulatory clearance. Please contact your local sales representative to check the availability in your country.