Physiology

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Proven outcomes.1,2,3
Superior value.
1,3

iFR is in a class of its own

iFR is the leading hyperemia-free physiologic index for measuring pressure in diagnostic and interventional procedures. Only offered by Philips, iFR is an evidence-based methodology that improves outcomes, saves time, and reduces patient discomfort.1,2,3 iFR Co-registration maps the physiologic measurements, directly onto the angiogram enabling more complete procedural guidance.
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iFR is recognized by key cardiovascular societies4,5,6,7
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Only iFR has clinically validated patient outcome data in the largest physiology studies ever1,2,3,9
Vessel
Only iFR has co-registration for advanced physiologic guidance
Omniwire cable new

iFR is now available on the world's first solid core pressure guide wire

 

With an all new workhorse design, only OmniWire combines confidence in wire performance with proven iFR outcomes and iFR Co-registration, making it easy to benefit from physiology throughout the case.

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DEFINE PCI

Unseen focal lesions cause residual ischemia9

Only iFR has co-registration for advanced physiologic guidance

Map iFR values directly onto the angiogram, so you can see precisely which parts of a vessel are causing ischemia

 

  • Plan your procedure with physiologic guidance
  • Better discern focal, serial, or diffuse disease
  • Determine precise lesion severity and location
  • Make length measurements without a cumbersome pullback device
  • Estimate the physiologic impact of a virtual stent
Available on the new Philips IntraSight interventional applications platform and as an upgrade to the Core systems.

Why should you use iFR

Co-registration?

Dr. Davies video

Improving PCI with iFR Co-registration

Dr. Justin Davies explains how iFR Co-registration can identify disease location and the likely impact of PCI before you stent.
Dr. Jeremias

Transforming how we do PCI with iFR Co-registration

Dr. Allen Jeremias explains the need to understand not just whether there is ischemia, but where it is when planning for PCI
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Introducing IntraSight
Smart. Simple. Seamless.

 

Introducing the all-new Philips IntraSight interventional applications platform where imaging, physiology, co-registration10 and software come together to facilitate optimal patient care. IntraSight offers a comprehensive suite of clinically proven modalities, such as, iFR/FFR, IVUS and co-registration10 to simplify complex interventions, speed routine procedures and provide improved patient care.

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Final CEE consent

1. Davies JE, et al., DEFINE-FLAIR: A Multi- Centre, Prospective, International, Randomized, Blinded Comparison of Clinical Outcomes and Cost Efficiencies of iFR and FFR Decision-Making for Physiological Guided Coronary Revascularization. New England Journal of Medicine, epub March 18, 2017.

2. Gotberg M, et al., Instantaneous Wave-Free Ratio Versus Fractional Flow Reserve Guided Intervention (IFR-SWEDEHEART): A Multicenter, Prospective, Registry-Based Randomized Clinical Trial. New England Journal of Medicine, epub March 18, 2017.

3. Patel M. “Cost-effectiveness of instantaneous wave-Free Ratio (iFR) compared with Fractional Flow Reserve (FFR) to guide coronary revascularization decision-making.” Late-breaking Clinical Trial presentation at ACC on March 10, 2018.  

4. Patel M, et al., ACC/AATS/AHA/ASE/ASNC/SCAI/SCCT/STS 2017 Appropriate Use Criteria for Coronary Revascularization in Patients with Stable Ischemic Heart Disease. J Am Coll Cardiol. 2017 May 2;69(17):2212-2241.

5. ACC CathPCI Hospital Registry.

6. Lofti A, et al. Focused update of expert consensus statement: Use of invasive assessments of coronary physiology and structure: A position statement of the society of cardiac angiography and interventions. Catheter Cardiovasc Interv. 2018;1–12.

7. 2018 ESC/EACTS Guidelines on myocardial revascularization: The task force on myocardial revascularization of the European society of cardiology (ESC) and European association for cardio-thoracic surgery (EACTS). Eur Heart J. 2018;00:1-96.

8. An iFR cut-point of 0.89 matches best with an FFR ischemic cut-point of 0.80 with a specificity of 87.8% and sensitivity of 73.0%. (From ADVISE II, and iFR Operator’s Manual 505-0101.23.

9. Jeremias A et al. The DEFINE PCI Trial: Blinded Physiological Assessment of Residual Ischemia after Successful Angiographic Percutaneous Coronary Intervention, presented at ACC 2019.
10. Co-registration tools available within IntraSight 7 configuration via SyncVision