Proven outcomes.^1,2,3^{Superior value.}^1,3

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iFR is in a class of its own

iFR is the leading hyperemia-free physiologic index for measuring pressure in diagnostic and interventional procedures. Only offered by Philips, iFR is an evidence-based methodology that improves outcomes, saves time, and reduces patient discomfort.^1,2,3 iFR Co-registration maps the physiologic measurements, directly onto the angiogram enabling more complete procedural guidance.

iFR is recognized in key industry guidelines

Only iFR has been included in both the AUC (ACC Appropriate Use Criteria)⁴ and NCDR (National Cardiovascular Data Registry).⁵
Only iFR has been designated as “definitely beneficial” by SCAI (Society of Cardiac Angiography and Interventions).⁶
Only iFR has received a Class 1A designation in the ESC (European Society of Cardiology) guidelines.⁷

Only iFR has clinically validated patient outcome data in the largest physiology studies ever

Proven outcomes

Validated in more than 4,500 patients^1,2
Consistent outcomes as with FFR^1,2
0.89 cut-point backed by data^1,2,8

Superior value

10% cost saving per patient³
10% reduction in procedure time^1,2
90% reduction in patient discomfort¹

Proven outcomes

Validated in more than 4,500 patients^1,2
Consistent outcomes as with FFR^1,2
0.89 cut-point backed by data^1,2,8

Superior value

10% cost saving per patient³
10% reduction in procedure time^1,2
90% reduction in patient discomfort¹

How do you know where to treat?

How do you know where to treat?

Play

DEFINE PCI

Unseen focal lesions cause residual ischemia¹⁰

Learn more

LAD deferral is safer with iFR⁹

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DEFINE PCI

Unseen focal lesions cause residual ischemia¹⁰

Learn more

LAD deferral is safer with iFR⁹

Learn more

Introducing IntraSight
Smart. Simple. Seamless.

Introducing the all-new Philips IntraSight interventional applications platform where imaging, physiology, co-registration¹¹ and software come together to facilitate optimal patient care. IntraSight offers a comprehensive suite of clinically proven modalities, such as, iFR/FFR, IVUS and co-registration¹¹ to simplify complex interventions, speed routine procedures and provide improved patient care.

Learn more about IntraSight

Only iFR has co-registration for advanced physiologic guidance

Learn more about iFR Co-registration

Map iFR values directly onto the angiogram, so you can see precisely which parts of a vessel are causing ischemia

Mapping of physiologic pressure drops onto the angiogram to better discern focal, serial or diffuse disease.
Precise lesion severity, location and length assessment.
Make length measurements without a cumbersome pull back device.
Physiologic impact of a virtual stent.
Plan your procedure with physiologic guidance.

Available on the new Philips IntraSight interventional applications platform and as an upgrade to the Core systems.

Why should you use iFR Co-registration?

Improving PCI with
iFR Co-registration

Dr. Justin Davies explains how iFR Co-registration can identify disease location and the likely impact of PCI before you stent.

Transforming how we do PCI with
iFR Co-registration

Dr. Allen Jeremias explains the need to understand not just whether there is ischemia, but where it is when planning for PCI.

DEFINE PCI results

1 in 4 patients leave the cath lab with post-PCI residual ischemia, mostly due to unseen focal lesions.¹⁰

View DEFINE PCI results

Experts discuss DEFINE PCI key findings

Watch Drs. Allen Jeremias, Gregg Stone, Habib Samady and Manesh Patel as they discuss the results of DEFINE PCI.

Watch experts discuss results

Why should you use iFR Co-registration?

Improving PCI with iFR Co-registration

Dr. Justin Davies explains how iFR Co-registration can identify disease location and the likely impact of PCI before you stent.

Transforming how we do PCI with iFR Co-registration

Dr. Allen Jeremias explains the need to understand not just whether there is ischemia, but where it is when planning for PCI

DEFINE PCI results

1 in 4 patients leave the cath lab with post-PCI residual ischemia, mostly due to unseen focal lesions.¹⁰

Learn more

Experts discuss DEFINE PCI key findings

Watch Drs. Allen Jeremias, Gregg Stone, Habib Samady and Manesh Patel as they discuss the results of DEFINE PCI.

Learn more

Where should
we treat?

Click on a letter to visually identify physiologically significant lesions

That is not the physiologically significant lesion.

Try again

Correct, that is the physiologically significant lesion.

Educational opportunities

Philips ELIITE Academy is focused on delivering high value and real-time strategic educational programs that meet the evolving needs of our customers. For more information on the available courses, please download our Medical Education brochure.

You can also visit www.philipseliiteacademy.com.

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1. Davies JE, et al., DEFINE-FLAIR: A Multi- Centre, Prospective, International, Randomized, Blinded Comparison of Clinical Outcomes and Cost Efficiencies of iFR and FFR Decision-Making for Physiological Guided Coronary Revascularization. New England Journal of Medicine, epub March 18, 2017.

2. Gotberg M, et al., Instantaneous Wave-Free Ratio Versus Fractional Flow Reserve Guided Intervention (IFR-SWEDEHEART): A Multicenter, Prospective, Registry-Based Randomized Clinical Trial. New England Journal of Medicine, epub March 18, 2017.

3. Patel M. “Cost-effectiveness of instantaneous wave-Free Ratio (iFR) compared with Fractional Flow Reserve (FFR) to guide coronary revascularization decision-making.” Late-breaking Clinical Trial presentation at ACC on March 10, 2018.

4. Patel M, et al., ACC/AATS/AHA/ASE/ASNC/SCAI/SCCT/STS 2017 Appropriate Use Criteria for Coronary Revascularization in Patients with Stable Ischemic Heart Disease. J Am Coll Cardiol. 2017 May 2;69(17):2212-2241.

5. ACC CathPCI Hospital Registry.

6. Lofti A, et al. Focused update of expert consensus statement: Use of invasive assessments of coronary physiology and structure: A position statement of the society of cardiac angiography and interventions. Catheter Cardiovasc Interv. 2018;1–12.

7. 2018 ESC/EACTS Guidelines on myocardial revascularization: The task force on myocardial revascularization of the European society of cardiology (ESC) and European association for cardio-thoracic surgery (EACTS). Eur Heart J. 2018;00:1-96.

8. An iFR cut-point of 0.89 matches best with an FFR ischemic cut-point of 0.80 with a specificity of 87.8% and sensitivity of 73.0%. (From ADVISE II, and iFR Operator’s Manual 505-0101.23.

9. Sen S, Ahmad Y, et al. Major Adverse Cardiac Events when an LAD lesion is deferred after physiological assessment by FFR or iFR: A sub-study of DEFINE FLAIR. J Am Coll Cardiol 2019.

10. Jeremias A et al. The DEFINE PCI Trial: Blinded Physiological Assessment of Residual Ischemia after Successful Angiographic Percutaneous Coronary Intervention, presented at ACC 2019.
11. Co-registration tools available within IntraSight 7 configuration via SyncVision

Proven outcomes.1,2,3 Superior value.1,3

iFR is in a class of its own

iFR is recognized in key industry guidelines

Only iFR has clinically validated patient outcome data in the largest physiology studies ever

DEFINE PCI

DEFINE PCI

Introducing IntraSight Smart. Simple. Seamless.

Only iFR has co-registration for advanced physiologic guidance

Why should you use iFR Co-registration?

Improving PCI with iFR Co-registration

Transforming how we do PCI with iFR Co-registration

DEFINE PCI results

Experts discuss DEFINE PCI key findings

Why should you use iFR Co-registration?

Improving PCI with iFR Co-registration

Transforming how we do PCI with iFR Co-registration

DEFINE PCI results

Experts discuss DEFINE PCI key findings

Where should we treat?

Educational opportunities

Contact information

Proven outcomes.^1,2,3^{Superior value.}^1,3

Introducing IntraSight
Smart. Simple. Seamless.

Improving PCI with
iFR Co-registration

Transforming how we do PCI with
iFR Co-registration

Where should
we treat?