Advanced Physiologic guidance with iFR Co-Registration
Image-guided therapy

iFR Co-registration

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Elevate your physiologic decision-making with iFR Co-registration

Only Philips iFR Co-registration helps you decide where to treat by mapping the iFR pull back directly onto the angiogram for a new dimension in PCI guidance.  Confident assessment: 38% of stenoses severity classifications changed when using iFR Co-registration compared to using angiography alone.2,3 Minimize unnecessary stent placement: iFR Co-registration helps identify lesions that will truly benefit from PCI. Tailored intervention: Obtain additional perspective on PCI planning by helping identify strategies for the most physiological gain.

Demonstrated results

  1. 1 in 4

    patients with successful PCI left the cath lab with residual ischemia

    1 in 4

    patients with successful PCI left the cath lab with residual ischemia

    (defined as iFR <0.90 residual DS <50% in any treated lesion).1

  2. 81.6%

    of patients with ischemia, were caused by an inapparent focal stenosis

    81.6%

    of patients with ischemia, were caused by an inapparent focal stenosis

    with residual ischemia, were caused by an untreated angiographically inapparent physiologically focal stenosis (≤ 15 mm).1

  3. 79%

    reduction in residual ischemia

    79%

    reduction in residual ischemia

    if all focal lesions had been successfully treated (24% to 5%).1

  4. 68%

    relative relative reduction in clinical events

    68%

    relative relative reduction in clinical events

    in clinical events at 1 year follow-up among patients achieving post-PCI iFR ≥ 0.95 (p-value=0.04).2

Virtually plan your PCI and predict results
Angiography provides a visual picture, but often lacks the detail needed for optimal PCI planning. Only Philips provides advanced physiologic guidance to help you determine not just whether to treat, but also where to treat, ensuring precise, patient-focused care.
1. Identify the precise locations causing ischemia - each yellow dot signifies a 0.01 drop
2. Plan your treatment, before a stent is even placed, with a virtual stent
3. Determine lesion lengths without need for a pullback device
4. Predict physiologic gain with iFR Estimate to determine the best treatment strategies
Advanced physiologic guidance with Philips iFR
Quickly and easily understand lesion-specific physiology
Quick iFR Co-registration graphically displays the iFR drop along the angiogram, highlighting which portion of the vessel is ischemic.
image of Diffuse disease
Make length measurements without a cumbersome pull back device
iFR Co-registration is calibrated for distance, so with a simple manual pullback you can make measurements on the angiogram and trend line.
Image of Focal disease
World’s first solid core pressure guide wire.7
With an all new workhorse design, only Philips OmniWire pressure wire combines confidence in wire performance with proven fire outcomes and iFR Co-registration, making it easy to benefit from physiology throughout the case.1, 5-6
View OmniWire
Image of OmniWire Standard Product
Footnotes
  1. Jeremias A, et al. Blinded Physiological Assessment of Residual Ischemia After Successful Angiographic Percutaneous Coronary Intervention: The DEFINE PCI Study. JACC Cardiovasc Interv. 2019;12(20):1991-2001.
  2. Patel M., et al. 1-Year outcomes of blinded physiological assessment of residual ischemia after successful PCI. JACC Cardiol Interv. 2022;15(1):52-61.
  3. Joseph T, Foley M, Al-Lamee R. Physiology and Intravascular Imaging Coregistration—Best of all Worlds? Intervent Cardiol Clin 2023;12:71–82.
  4. Matsuo A, Kasahara T, Ariyoshi M, et al. Utility of angiography–physiology coregistration maps during percutaneous coronary intervention in clinical practice. Cardiovasc Interv Ther 2021;36(2):208–18.
  5. Davies JE, et al., Use of the Instantaneous Wave-free Ratio or Fractional Flow Reserve in PCI. N Engl J Med. 2017 May 11;376(19):1824-1834.
  6. Gotberg M, et al., iFR-SWEDEHEART Investigators. Instantaneous Wave-free Ratio versus Fractional Flow Reserve to Guide PCI. N Engl J Med. 2017 May 11;376(19):1813-1823.
  7. Data on file D000410086_A, D000485394_A
Disclaimer
Results are specific to the institution where they were obtained and may not reflect the results achievable at other institutions. Results in other cases may vary.