The WE-TRUST (Workflow Optimization to Reduce Time to Endovascular Reperfusion for Ultra-fast Stroke Treatment) trial investigates the clinical impact of the DTAS approach, which combines stroke diagnosis and treatment in a single angio suite session. Enabled by a cone-beam CT (CBCT) imaging tool already integrated into interventional angio suite systems such as Philips Image Guided Therapy System – Azurion, the DTAS approach can potentially reduce the time to treatment for early time-window stroke patients (less than six hours after stroke onset). Every 30 minutes of delay before treatment reduces the chance of a good outcome by 14% , and every hour ages the brain by 3.6 years compared to a normally aging brain .
“At Philips, we are convinced that direct-to-angio workflows, in which stroke patients are diagnosed and treated in the same room, has the potential to save precious minutes and even more precious brain function,” said Atul Gupta, Chief Medical Officer for Image Guided Therapy at Philips. “While that belief is already supported by the results of several single-center studies, we need a clinical trial with the scale and reach of WE-TRUST to determine whether direct-to-angio has the potential to become the gold standard for stroke care.”
WE-TRUST is a multicenter, prospective, randomized controlled, open-label, blinded-endpoint trial that aims to engage 16 leading strokes sites and enroll a total of more than 500 patients across the United States, Brazil, Argentina, the Netherlands, France, Germany, Spain and Turkey. More information about the study can be found at wetrust-study.com.
Recently, Philips announced that the results of a health economics analysis recently published in the Journal of NeuroInterventional Surgery (JNIS) show that Philips’ direct-to-angio treatment pathway for stroke patients can save more than USD 3,000 per patient.
*The WE-TRUST (Workflow Optimization to Reduce Time to Endovascular Reperfusion for Ultra-fast Stroke Treatment) clinical trial is sponsored by Philips
 World Stroke Organization (WSO): Global Stroke Fact Sheet 2022 (https://www.world-stroke.org/assets/downloads/WSO_Global_Stroke_Fact_Sheet.pdf)
 U.S. National Stroke Association