The American Dental Association's website indicates that there is insufficient clinical evidence to support concern that bacterial growth on toothbrushes will lead to specific adverse oral or systemic health effects.

The oral cavity harbours hundreds of different types of microorganisms (germs), some of which are transferred to a toothbrush during use. Microorganisms in the environment may also camp on a toothbrush. Sanitisation and storage of brush heads in between uses with the Philips Sonicare UV Sanitiser should reassure concerned users that they are optimising their oral hygiene regiment for improved oral health.